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Rutin inhibits ERS in H9C2 cells treated with HG. Western blotting analysis was used to determine the expression levels of ERS related proteins. ERS, endoplasmic reticulum stress; HG, high glucose; NG, normal glucose; MA, mannitol; HSPA5, heat shock protein A5; IRE1α, insulin response element 1α; XBP1, X-box binding protein 1; CHOP, C/EBP-homologous protein; ATF6, activating transcription factor 6. ***P<0.001 vs. MA. #P<0.05, ##P<0.01, ###P<0.001 vs. HG.
