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. Author manuscript; available in PMC: 2021 Jul 15.

Published in final edited form as: J Pharmacokinet Pharmacodyn. 2021 Jan 4;48(2):225–239. doi: 10.1007/s10928-020-09726-9

Fig. 2 — Average glucose flux measurements from healthy nondiabetic resting subjects (blue) and exercising subjects (orange). (top) Measured rate of meal appearance (Ra_meal), which is used as an input to the model. (bottom) Measured endogenous glucose production (EGP_data) which is not an input but is used for comparison to the EGP model predictions (see Fig. 6). Meal ingestion occurs at t= 0. The exercising subjects have four 15 min exercise bouts from t = 120–195 shown by shaded regions (shaded regions do not apply to resting subjects). During exercise EGP_data is seen to increase rapidly. Error bars indicate the standard error of the mean (SEM)

Fig. 2 — Average glucose flux measurements from healthy nondiabetic resting subjects (blue) and exercising subjects (orange). (top) Measured rate of meal appearance (Ra_meal), which is used as an input to the model. (bottom) Measured endogenous glucose production (EGP_data) which is not an input but is used for comparison to the EGP model predictions (see Fig. 6). Meal ingestion occurs at t= 0. The exercising subjects have four 15 min exercise bouts from t = 120–195 shown by shaded regions (shaded regions do not apply to resting subjects). During exercise EGP_data is seen to increase rapidly. Error bars indicate the standard error of the mean (SEM)