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. 2021 Jul 15;19:211. doi: 10.1186/s12951-021-00902-8

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© The Author(s) 2021

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 1 — In vivo biodistribution of a GO-based nanosystem in a mouse tumor xenograft model. a Fluorescence imaging of tumor-bearing mice after intravenous injection of a fluorescence-labeled GO-based nanosystem at different times. b The GO-based nanosystem mainly accumulated in tumors, which showed the highest fluorescence intensity. c Mean fluorescence signal indicating the GO-based nanosystem distribution in tumors and other major organs [18]. Reprinted from Journal of Controlled Release, 326, Sahu A, Min K, Jeon J, Yang HS, Tae G, Catalytic nanographene oxide with hemin for enhanced photodynamic therapy, 442–454, 2020, with permission from Elsevier