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. 2021 Jul 1;11:710899. doi: 10.3389/fonc.2021.710899

Figure 1.

Figure 1

The morphology of perineural invasion and axonogenesis in PCa and the benign prostate. (A, B) Different forms of perineural invasion and small nerves within the cancerous infiltration (PGP 9.5, 200x). (C) Multiple axons and small nerves within the stroma of the benign prostate (PGP 9.5, 400x). (D, E) Axons within the neoplastic infiltrate located in the stroma and surrounding cancer cells (D, TH, 600x), (E, TH, 400x). (F) High neural density in the surrounding benign prostate with axons growing into the cancer tissue of high Gleason score PCa (PGP 9.5, 200x).