Table 2.
ND and PNI in the study group according to Grade Group, pT stage and ERG status.
| PGP ND | TH ND | PNI | ||||
|---|---|---|---|---|---|---|
| PCa | (structures/field of view) | p-value | (structures/field of view) | p-value | N (%) | p-value |
| Range: | 1.5-87.4 | 1-27.4 | ||||
| Average: | 31.1 | 9.9 | ||||
| Median: | 31.45 (95% CI 24.3-36) | 8.40 (95% CI 6.97-10.1) | ||||
| pT | Median | |||||
| pT2 | 26.50 (95% CI 1.5-73.9) | p=0.28 | 8.00 (95% CI 1-27.4) | p=0.96 | 37 (66) | p=0.02 |
| pT3 | 34.05 (95% CI 3.4-87.4) | 8.40 (95% CI 1-26.4) | 19 (34) | |||
| GG | ||||||
| 1 | 33.50 (95% CI 10.34-45.47) | p=0.04* | 15.90 (95% CI 4.37-19.89) | 5 (41.66) | p<0.01** | |
| 2 | 28.60 (95% CI 21.02-36.05) | 8.00 (95% CI 5.13-9.26) | 27 (81.82) | |||
| 3 | 37.30 (95% CI 11.10-53.97) | 12.90 (95% CI 3.74-18.79) | 10 (76.92) | |||
| 4 | 35.10 (95% CI 19.40-50.18) | 10.20 (95% CI 4.19-22.40) | 7 (100) | |||
| 5 | 24.17 (95% CI 17.28-41.64) | 7.13 (95% CI 5.57-10.56) | 7 (87.50) | |||
| ERG | ||||||
| Positive*** | 36.00 (95% CI 29.38-42.62) | p=0.03 | 8.80 | PNI + PNI - | p=0.03 | |
| Negative | 26.58 (95% CI 21.10-32.05) | 8.00 | 31 (42.46) 4 (5.48) | |||
| 25 (34.25) 13 (17.81) | ||||||
| Periphery | p-value | p-value | ||||
| Range: | 5-143 | 1-100 | ||||
| Average: | 46.2 | 26.89 | ||||
| Median: | 42 (95% CI 33.8-55) | 21.5 (95% CI 17.9-29.5) | ||||
| pT | ||||||
| pT2 | 42.50 (95% CI 5-124) | p=0.85 | 25.00 (95% CI 1-100) | p=0.49 | ||
| pT3 | 40.00 (95% CI 7-143) | 20.75 (95% CI 1-66) | ||||
| BP | ||||||
| Range: | 10.2-114.9 | 3.5-185 | ||||
| Average: | 36.15 | 32.7 | ||||
| Median: | 38.15 (95% CI 15.2-61.2) | 15.60 (95% CI 10-40.79) | ||||
GG, Grade Group; PNI, perineural invasion; * for GG1 vs. GG2, ** for GG1 vs. GG2-5,*** the mean.