Table 6.

Nitric oxide-release properties from S-nitrosothiol NO donor-modified HP-DTT polyesters in PBS or 500 μM DTPA-supplemented PBS (37 °C, pH 7.4).^a

DTPA	Light	G2-HP-DTT/NO			G3-HP-DTT/NO			G4-HP-DTT/NO
		t[NO]b (μmol mg−1)	t1/2c (min)		t[NO]b (μmol mg−1)	t1/2c (min)		t[NO]b (μmol mg−1)	t1/2c (min)
Yes	No	1.47 ± 0.24	56 ± 24		1.26 ± 0.39	70 ± 29		1.53 ± 0.04	171 ± 56
Yes	Yes	1.43 ± 0.10	42 ± 12		1.05 ± 0.20	42 ± 15		1.43 ± 0.10	132 ± 35
No	No	1.73 ± 0.17	7 ± 2		1.47 ± 0.32	4 ± 2		1.83 ± 0.18	7 ± 3
No	Yes	1.69 ± 0.24	6 ± 3		1.50 ± 0.42	3 ± 1		1.90 ± 0.22	9 ± 3

^an ≥ 3 separate syntheses;

^bTotal NO storage per milligram polyesters;

^cHalf-life of NO release.