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. 2021 Jun 30;12:617628. doi: 10.3389/fendo.2021.617628

Table 3.

Characteristics of medication application by allocated clusters.

All SIDD SIRD MOD MARD P value
Medication, N (%) 486 (100) 75 (15) 106 (22) 109 (22) 196 (40)
Metformin, N (%) 362 (74) 54 (72) 78 (74) 94 (86) 136 (69) 0.012
SU, N (%) 60 (12) 9 (12) 15 (14) 12 (11) 24 (12) 0.917
TZDs, N (%) 15 (3) 1 (1) 5 (5) 6 (6) 3 (2) 0.139
AGI,N (%) 223 (46) 43 (57) 40 (38) 40 (37) 100 (51) 0.006
DPP-4,N (%) 270 (56) 37 (49) 53 (50) 54 (50) 126 (64) 0.017
SGLT-2,N (%) 84 (17) 10 (13) 18 (17) 21 (19) 35 (18) 0.760
GLP-1,N (%) 24 (5) 1 (1) 4 (4) 17 (16) 2 (1) <0.001
Glinides, N (%) 21(4) 3 (4) 8 (8) 5 (5) 5 (3) 0.239
Insulin, N (%) 192 (40) 57 (76) 21 (20) 49 (50) 65 (33) <0.001
Statins, N (%) 326 (67) 61 (81) 62 (59) 78 (72) 125 (64) 0.006
AHT, N (%) 195 (40) 34 (45) 51 (48) 39 (36) 71 (36) 0.124

All values were N (%). SU, sulphonylurea; TZDs, thiazolidinediones; AGI, α-glucosidase inhibitor; DPP4-I, dipeptidyl peptidase 4 inhibitors; SGLT2, sodium-glucose co-transporter 2 inhibitors; GLP-1, glucagon-like peptide-1; AHT, antihypertensive treatment (includes diuretics, β-blockers, and renin–angiotensin system inhibitors); SIDD, severe insulin-deficient diabetes; SIRD, severe insulin-resistant diabetes; MOD, mild obesity-related diabetes; MARD, mild age-related diabetes.