Table 3.
Relevant factors associated with delisting due to death or clinical deterioration on adjusted analysis
| Risk Factor | Hazard Ratio [95% CI] | p-value |
|---|---|---|
| Age, per year | 1.02 [1.02-1.02] | <0.001 |
| Male | 0.86 [0.84-0.88] | <0.001 |
| Race | ||
| White | Reference | |
| Black | 1.06 [1.02-1.11] | 0.01 |
| Hispanic | 1.05 [1.02-1.09] | 0.01 |
| Asian | 0.93 [0.88-1.00] | 0.04 |
| Other* | 1.05 [0.95-1.15] | 0.37 |
| Education level | ||
| Less than high school | Reference | |
| High school diploma/GED | 0.98 [0.94-1.03] | 0.51 |
| Attended college | 0.94 [0.90-0.99] | 0.03 |
| Associate's/Bachelor's degree | 0.89 [0.84-0.94] | <0.001 |
| Graduate degree | 0.83 [0.77-0.88] | <0.001 |
| Insurance type | ||
| Private | Reference | |
| Medicare | 1.20 [1.17-1.24] | <0.001 |
| Medicaid | 1.20 [1.16-1.24] | <0.001 |
| Employed at listing | 0.81 [0.78-0.84] | <0.001 |
| Dialysis twice in prior week at listing | 2.22 [2.10-2.34] | <0.001 |
| MELD score at listing, per point | 0.99 [0.99-0.99] | <0.001 |
| Liver disease etiology | ||
| Alcoholic liver disease | Reference | |
| Acute liver failure | 0.98 [0.91-1.06] | 0.60 |
| Cholestatic liver disease | 0.86 [0.81-0.90] | <0.001 |
| Hepatitis B | 0.87 [0.78-0.95] | 0.004 |
| Hepatitis C | 0.97 [0.94-1.01] | 0.12 |
| HCC | 0.71 [0.68-0.75] | <0.001 |
| NASH | 1.02 [0.97-1.06] | 0.48 |
| Other | 1.04 [1.01-1.08] | 0.03 |
| Encephalopathy | ||
| None | Reference | |
| Grade 1-2 | 1.04 [1.02-1.07] | 0.003 |
| Grade 3-4 | 1.26 [1.19-1.32] | <0.001 |
| Ascites | ||
| Absent | Reference | |
| Slight | 1.19 [1.16-1.23] | <0.001 |
| Moderate | 1.25 [1.20-1.31] | <0.001 |
| UNOS Region | ||
| Region 1 | Reference | |
| Region 2 | 0.83 [0.78-0.88] | <0.001 |
| Region 3 | 0.39 [0.36-0.41] | <0.001 |
| Region 4 | 0.85 [0.80-0.90] | <0.001 |
| Region 5 | 0.92 [0.87-0.98] | 0.004 |
| Region 6 | 0.69 [0.63-0.76] | <0.001 |
| Region 7 | 0.77 [0.72-0.82] | <0.001 |
| Region 8 | 0.71 [0.67-0.76] | <0.001 |
| Region 9 | 0.99 [0.93-1.05] | 0.67 |
| Region 10 | 0.56 [0.53-0.60] | <0.001 |
| Region 11 | 0.51 [0.48-0.55] | <0.001 |
*
Other race includes American Indian, Alaska Native, Native Hawaiian, Pacific Islander and multiracial. All continuous variables reported as median (IQR). All categorical variables reported as N (%). GED: general educational development; HCC: hepatocellular carcinoma