Table 3. Clinical and laboratory data in relation to AKI in patients with COVID-19.
| Variable | AKI | Non AKI | P-value |
|---|---|---|---|
| Clinical characteristics | |||
| Age (years) | 68.7 (21–95) | 61.8 (18–95) | 0.074* |
| Male patients (n/%) | 28 (62.2) | 89 (60.1) | 0.001* |
| Diabetes (N/%) | 21 (46.7) | 74 (50) | 0.003* |
| Hypertension (N/%) | 18 (40) | 47 (31.8) | 0.001* |
| Clinical presentation | |||
| Fever and cough (N/%) | 19 (42.2) | 45 (30.4) | 0.041* |
| Fever (N/%) | 3 (6.7) | 34 (23) | 0.033* |
| Shortness of breath (N/%) | 23 (51.1) | 69 (46.6) | 0.001* |
| Cardiac diseases (N/%) | 1 (2.2) | 11 (7.4) | 0.183 |
| Severity | |||
| Critical | 33 (73.3) | 22 (14.9) | 0.003* |
| Severe | 12 (26.7) | 12 (8.1) | 0.001* |
| Moderate | 0 (0) | 114 (77) | 0.003* |
| ICU admission | |||
| Yes | 33 (73.3) | 22 (14.9) | 0.001* |
| No | 12 (26.7) | 126 (85.10) | 0.001* |
| Admission (days) | 19.7 (7–45) | 20.3 (7–48) | 0.530 |
| Laboratory data | |||
| CRP (0–3.3 mg/L) | 87.8 (14–211) | 69.3 (1–285) | 0.348 |
| ESR (0–29) | 72.7 (23–111) | 69.3 (16–120) | 0.111 |
| D dimer (0–0.5 mg/L) | 2.7 (0.2–15.2) | 3.4 (0–35) | 0.002* |
| WBCs (4–10 × 10^3/μL) | 11.3 (2.7–50.6) | 10.4 (2.5–27.5) | 0.298 |
| Lymphocytes(1–3 × 10^3/μL) | 1.5 (0.2–6.8) | 1.5 (0.3–12.2) | 0.548 |
| Neutrophils (1.8–7.7 × 10^3/μL) | 8.4 (1.5–44.5) | 7.9 (1–2.4) | 0.481 |
| Platelets (150–410 × 10^3/μL) | 217.8 (77–759) | 287.6 (53–1074) | 0.392 |
| Hemoglobin(11–16 g/dL) | 12 (6.9–15.7) | 12.0 (3.4–17.2) | 0.184 |
| RBCs (4–6 × 10^6/μL) | 4.4 (2.5–5.7) | 4.3 (2–6) | 0.007* |
| PT | 13.9 (10.5–22.5) | 14.3 (10–45) | 0.521 |
| AST (5–41 U/L) | 41.6 (14–208) | 81.9 (8–4933) | 0.334 |
| ALT (5–41 U/L) | 34.6 (6–167) | 50.36 (2–1825) | 0.381 |
| ALP (50–140 U/L) | 94.7 (27–313) | 115.8 (4–471) | 0.672 |
| Serum creatinine (44–116/μmol/L) | 221.5 (120–342) | 91.43 (34–112) | 0.002* |
| Serum urea (2.76–8.07 mmol/L) | 18.6 (11.8–39.9) | 8.997 (1.8–41.7) | 0.004* |
| Lactate dehydrogenase (100–190 U/L) | 369.89 (147–815) | 447.8 (90–7054) | 0.393 |
| Serum albumin (34–35G/L) | 33.9 (18–50.1) | 33.35 (16–47) | 0.131 |
| Total protein (64–86 G/L) | 70.9 (40–80.6) | 69.06 (30–89) | 0.64 |
| Sodium (135–145 mmol/L) | 134 (11–151) | 136.2 (136–150) | 0.205 |
| Amylase (28–100 U/L) | 80.2 (10–443) | 77.51 (10–801) | 0.345 |
| Outcome | |||
| Living (N/%) | 12 (24.4) | 124 (83.8) | 0.001* |
| Dead (N/%) | 33 (75.6) | 24 (16.2) | 0.003* |
*Significance was set at P< 0.05.