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. 2021 Jul 15;16(7):e0254887. doi: 10.1371/journal.pone.0254887

Table 2. Averages of clinical baseline parameters and evolution of heart rate and respiratory rate of dogs with stage B2 and C myxomatous mitral valve disease with omega-3 dietary supplementation or not for 12 months.

Control Omega-3
Variables Times n Averages n Averages p* p**
HR (bpm) T0 13 149.00 ± 28.00 16 154.00 ± 45.00 0.363 0.983
T3 10 144.00 ± 23.00 10 146.00 ± 40.00 0.853
T6 9 139.00 ± 27.00 8 138.00 ± 29.00 0.673
T9 9 137.00 ± 14.00 8 144.00 ± 32.00 0.606
T12 7 140.00 ± 28.00 6 148.00 ± 30.00 0.755
p*** 0.971 0.711
RR (mpm) T0 13 109.00 ± 63.00 16 93.00 ± 55.00 0.525 0.370
T3 10 64.00 ± 49.00 10 108.00 ± 56.00 0.853
T6 9 64.00 ± 40.00 8 84.00 ± 56.00 0.370
T9 9 70.00 ± 58.00 8 85.00 ± 61.00 0.167
T12 7 69.00 ± 50.00 6 111.00 ± 43.00 0.530
p*** 0.176 0.676

HR: Heart rate; bpm: Beats per minute; RR: Respiratory rate; mpm: Movements per minute; p*: Difference between treatments; p**: Difference between times; p***: Difference in treatment by time interaction Kruskal-Wallis test at 5% of significance.