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. 2021 Jul 2;17(7):e1009640. doi: 10.1371/journal.pgen.1009640

Fig 6. Sensitivity analysis of significantly perturbed metabolites (s-SPMs) after glucose addition.

Fig 6

A) Venn diagram of subsets of s-SPMs, before and after glucose addition for each mutant (mutantH-mutantL) and wildtype (wtH-wtL). Upper semicircle shows up-regulated s-SPMs and lower semicircle shows down-regulated s-SPMs. Numbers in parenthesis are shared s-SPMs regulated in the opposite direction, placed in the area corresponding to the direction of regulation. Subset of s-SPMs used for ORA analysis that are B) unique to gpa2; C) shared and changed in the opposite direction. Shared s-SPMs changed in the same direction and s-SPMs unique to asc1 are not over-represented in any pathway and are therefore not shown. Listed are all pathways and their functional categories with adjusted p-value <0.05.