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A: relationship between minute ventilation and V̇co2 in the mouse shown in Fig. 2 and in one β-arr2-deficient mouse (data obtained over 1 h). The spontaneous change in breathing was significantly correlated to the metabolic status. B: regression lines obtained in all of the mice (control and β-arr2-deficient mice). Arrb2tm1Rjl, Arrb2 knockout mice; β-arr2, β arrestin 2.
