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. 2021 Mar 3;125(4):1396–1407. doi: 10.1152/jn.00711.2020

Figure 9.

Figure 9.

Example of the effects of an injection of the highest dose of fentanyl (60 mg/kg ip) on instantaneous respiratory flow (V̇) in a β-arr2-deficient mouse. This mouse presented a terminal apnea within 5 min. This type of response was observed in 1 out of 20 control mice and 8 out of 20 β-arr2-deficient animals. β-arr2, β arrestin 2.