Table 4.

Risk of Early-onset Bloodstream Infection by Baseline Clinical and Demographic Characteristics Among Neonates Included in the Early Cohort

Characteristic	Odds Ratio	95% CI	P Value	Adjusted Odds Ratio	95% CI	P Value
Male sex	0.77	.45–1.32	.343	0.71	.41–1.22	.209
Preterm, <37 weeks' gestation	1.62	.86–3.06	.136	1.23	.54–2.81	.616
Low birth weight	1.53	.79–2.97	.210	1.31	.54–3.17	.545
Multiple gestation	0.58	.21–1.60	.289	0.57	.20–1.63	.296
Outborn	2.40	1.12–5.13	.025	1.87	.84–4.15	.126
Cesarean delivery	0.69	.40–1.22	.203	0.81	.45–1.44	.468
Positive-pressure ventilation at delivery	2.28	1.31–3.96	.004	1.60	.87–2.95	.130
Any respiratory support on admission	4.54	2.13–9.67	<.001	2.20	.92–5.26	.074
Central line on admission	0.89	.40–2.00	.783	0.43	.16–1.17	.098
Pressors on admission	3.47	1.95–6.19	<.001	2.45	1.29–4.64	.006
Antibiotics on admission	3.69	2.02–6.74	<.001	2.00	1.00–3.98	.049

Logistic regression performed for select baseline characteristics in neonates included in the early cohort (n = 3341). Individual variables and their relationship with early-onset bloodstream infection (n = 55) were assessed using univariate logistic regression and multivariable logistic regression. Multiple imputation was used to account for missing data. P values <.05 were considered statistically significant and are in bold.

Abbreviation: CI, confidence interval.