Table 5.

Risk of Late-onset Bloodstream Infection by Baseline Clinical and Demographic Characteristics Among Neonates Included in the Late Cohort

	Odds Ratio	95% CI	P Value	Adjusted Odds Ratio	95% CI	P Value
Male sex	0.84	.62–1.14	.256	0.80	.58–1.10	.164
Preterm, <37 weeks’ gestation	2.83	1.84–4.35	<.001	1.52	.93–2.50	.095
Low birth weight	1.80	1.21–2.67	.004	1.21	.71–2.07	.483
Multiple gestation	1.35	.87–2.09	.185	1.07	.67–1.72	.773
Outborn	2.66	1.87–3.80	<.001	2.65	1.80–3.90	<.001
Cesarean delivery	0.96	.71–1.31	.802	1.02	.73–1.40	.925
Positive-pressure ventilation at delivery	1.41	.98–2.01	.064	0.85	.58–1.26	.422
Any respiratory support on admission	3.29	2.30–4.71	<.001	1.70	1.11–2.60	.015
Central line on admission	4.14	2.85–6.03	<.001	2.72	1.77–4.19	<.001
Pressors on admission	2.29	1.59–3.31	<.001	1.15	.76–1.76	.505
Antibiotics on admission	4.35	3.04–6.23	<.001	2.55	1.69–3.84	<.001

Logistic regression performed for select baseline characteristics in neonates included in the late cohort (n = 3178). Individual variables and their relationship with late-onset bloodstream infection (n = 176) were assessed using univariate logistic regression and multivariable logistic regression. Multiple imputation was used to account for missing data. P values <.05 were considered statistically significant and are in bold.

Abbreviation: CI, confidence interval.