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. 2020 Jun 21;73(2):e330–e336. doi: 10.1093/cid/ciaa826

Table 1.

Clinical Performance of the Mp1p Enzyme Immunoassay in 889 Study Participants, Including 372 Participants With Culture-proven Talaromycosis and 517 Non-talaromycosis Control Participants

ODcutoff = 0.5 Talaromycosis Cases Non-talaromycosis Controls Sum
TmAg positive
OD ≥0.5
TP
321
FP
10
331
TmAg negative
OD <0.5
FN
51
TN
507
558
Sum 372 517 889
Diagnostic Features Diagnostic Values,
No. (%)
(95% CI)
Sensitivity 321/372 (86.3%) (82.3%–89.5%)
Specificity 507/517 (98.1%) (96.3%–99.0%)
Positive likelihood ratio 0.86310.981=45
Negative likelihood ratio 10.8630.981=0.14

Abbreviations: FN, false negative; FP, false positive; OD, optical density; TmAg, Talaromyces marneffei antigen; TN, true negative; TP, true positive.