Table 4.
Sensitivity Analyses, Relative Risk for Mortality, and Natural Decline in QALY Scores With Aging Among Patients When They Served as Their Own Controls
| Analysis | QALY Differences | QALY Differences, SE | P | 95% Confidence Interval (Lower-Upper) |
|---|---|---|---|---|
| Unadjusted results | ||||
| Baseline 30-day QALYs | 0.0101 | 0.0008 | <.001 | .0085–.0118 |
| Mortality relative risk = 1 | 0.0102 | 0.0008 | <.001 | .0086–.0119 |
| Mortality relative risk = 4 | 0.0100 | 0.0008 | <.001 | .0084–.0115 |
| No natural decline | 0.0102 | 0.0008 | <.001 | .0086–.0118 |
| Doubled natural decline | 0.0101 | 0.0008 | <.001 | .0085–.0117 |
| Baseline 90-day QALYs | 0.0296 | 0.0027 | <.001 | .0244–.0349 |
| Mortality relative risk = 1 | 0.0305 | 0.0027 | <.001 | .0252–.0357 |
| Mortality relative risk = 4 | 0.0279 | 0.0027 | <.001 | .0226–.0332 |
| No natural decline | 0.0298 | 0.0026 | <.001 | .0247–.0349 |
| Doubled natural decline | 0.0294 | 0.0027 | <.001 | .0241–.0347 |
| Baseline 180-day QALYs | 0.0631 | 0.0050 | <.001 | .0533–.0728 |
| Mortality relative risk = 1 | 0.0665 | 0.0051 | <.001 | .0565–.0764 |
| Mortality relative risk = 4 | 0.0564 | 0.0052 | <.001 | .0462–.0665 |
| No natural decline | 0.0637 | 0.0050 | <.001 | .0540–.0734 |
| Doubled natural decline | 0.0624 | 0.0051 | <.001 | .0524–.0724 |
| Baseline 365-day QALYs | 0.1424 | 0.0095 | <.001 | .1237–.1611 |
| Mortality relative risk = 1 | 0.1561 | 0.0099 | <.001 | .1366–.1756 |
| Mortality relative risk = 4 | 0.1161 | 0.0102 | <.001 | .0961–.1361 |
| No natural decline | 0.1447 | 0.0099 | <.001 | .1254–.1640 |
| Doubled natural decline | 0.1401 | 0.0098 | <.001 | .1210–.1592 |
| Adjusted results | ||||
| Baseline 30-day QALYs | 0.0108 | 0.0009 | <.001 | .0091–.0125 |
| Mortality relative risk = 1 | 0.0110 | 0.0009 | <.001 | .0093–.0127 |
| Mortality relative risk = 4 | 0.0105 | 0.0009 | <.001 | .0088–.0125 |
| No natural decline | 0.0109 | 0.0008 | <.001 | .0092–.0125 |
| Doubled natural decline | 0.0108 | 0.0009 | <.001 | .0091–.0125 |
| Baseline 90-day QALYs | 0.0303 | 0.0027 | <.001 | .0250–.0356 |
| Mortality relative risk = 1 | 0.0317 | 0.0027 | <.001 | .0264–.0371 |
| Mortality relative risk = 4 | 0.0275 | 0.0027 | <.001 | .0223–.0328 |
| No natural decline | 0.0305 | 0.0026 | <.001 | .0253–.0356 |
| Doubled natural decline | 0.0301 | 0.0027 | <.001 | .0248–.0355 |
| Baseline 180-day QALYs | 0.0605 | 0.0056 | <.001 | .0494–.0715 |
| Mortality relative risk = 1 | 0.0660 | 0.0057 | <.001 | .0547–.0772 |
| Mortality relative risk = 4 | 0.0502 | 0.0057 | <.001 | .0389–.0614 |
| No natural decline | 0.0610 | 0.0055 | <.001 | .0501–.0718 |
| Doubled natural decline | 0.0599 | 0.0058 | <.001 | .0485–.0713 |
| Baseline 365-day QALYs | 0.1302 | 0.0124 | <.001 | .1060–.1545 |
| Mortality relative risk = 1 | 0.1512 | 0.0126 | <.001 | .1266–.1758 |
| Mortality relative risk = 4 | 0.0935 | 0.0128 | <.001 | .0684–.1186 |
| No natural decline | 0.1319 | 0.0122 | <.001 | .1081–.1558 |
| Doubled natural decline | 0.1285 | 0.0128 | <.001 | .1034–.1536 |
Abbreviation: QALY, quality-adjusted life-year.