Table 1.
Description of the cohort: sample size, number of patients hospitalized for COVID-19 and number of COVID-19-related deaths in hospital.
| Number | Number of hospitalizations with COVID-19 | Number of in-hospital death with COVID-19 | ||||
|---|---|---|---|---|---|---|
| 66,050,590 | colomn % | 87,809 | % (within stratum) | 15,661 | % (within stratum) | |
| Characteristics sociodemographic | ||||||
| Age (years) - mean (SD) | 43 (24) | 67 (19) | 80 (12) | |||
| Age - no (%) | ||||||
| < 5 | 2,928,823 | 4·4% | 161 | 0·01% | 1 | 0·00% |
| 5 - 9 | 3,912,876 | 5·9% | 115 | 0·00% | 1 | 0·00% |
| 10 - 14 | 4,005,913 | 6·1% | 133 | 0·00% | 0·00% | |
| 15 - 19 | 3,881,938 | 5·9% | 393 | 0·01% | 2 | 0·00% |
| 20 - 24 | 3,619,129 | 5·5% | 1,123 | 0·03% | 3 | 0·00% |
| 25 - 29 | 3,727,718 | 5·6% | 1,772 | 0·05% | 7 | 0·00% |
| 30 - 34 | 4,100,006 | 6·2% | 2,285 | 0·06% | 19 | 0·00% |
| 35 - 39 | 4,209,706 | 6·4% | 2,780 | 0·07% | 45 | 0·00% |
| 40 - 44 | 4,113,768 | 6·2% | 3,252 | 0·08% | 57 | 0·00% |
| 45 - 49 | 4,416,462 | 6·7% | 4,554 | 0·10% | 100 | 0·00% |
| 50 - 54 | 4,417,700 | 6·7% | 5,746 | 0·13% | 273 | 0·01% |
| 55 - 59 | 4,366,478 | 6·6% | 6,705 | 0·15% | 417 | 0·01% |
| 60 - 64 | 4,084,019 | 6·2% | 7,381 | 0·18% | 711 | 0·02% |
| 65 - 69 | 3,846,402 | 5·8% | 7,478 | 0·19% | 1,119 | 0·03% |
| 70 - 74 | 3,690,137 | 5·6% | 8,662 | 0·23% | 1,655 | 0·04% |
| 75 - 79 | 2,301,857 | 3·5% | 7,548 | 0·33% | 1,795 | 0·08% |
| 80 - 84 | 1,893,802 | 2·9% | 8,727 | 0·46% | 2,657 | 0·14% |
| 85 - 89 | 1,449,669 | 2·2% | 9,562 | 0·66% | 3,303 | 0·23% |
| 90 - 110 | 1,084,187 | 1·6% | 9,432 | 0·87% | 3,496 | 0·32% |
| Sex | ||||||
| Women | 34,328,810 | 52·0% | 41,043 | 0·12% | 6,302 | 0·018% |
| Men | 31,721,780 | 48·0% | 46,766 | 0·15% | 9,359 | 0·030% |
| Regions - no (%) | ||||||
| Ile de France | 11,979,153 | 291·2% | 30,009 | 0·25% | 5,612 | 0·05% |
| Grand Est | 5,399,178 | 131·2% | 12,939 | 0·24% | 2,894 | 0·05% |
| Hauts-de-France | 5,889,172 | 143·2% | 8,852 | 0·15% | 1,729 | 0·03% |
| Auvergne-Rhône-Alpes | 7,930,539 | 192·8% | 8,535 | 0·11% | 1,499 | 0·02% |
| Bourgogne-Franche-Comté | 2,715,812 | 66·0% | 4,303 | 0·16% | 872 | 0·03% |
| Centre-Val-de-Loire | 2,533,193 | 61·6% | 2,264 | 0·09% | 408 | 0·02% |
| Provence-Alpes-Côte d'Azur | 5,211,475 | 126·7% | 7,971 | 0·15% | 772 | 0·01% |
| Occitanie | 5,908,406 | 143·6% | 3,161 | 0·05% | 444 | 0·01% |
| Nouvelle-Aquitaine | 5,951,085 | 144·7% | 2,724 | 0·05% | 388 | 0·01% |
| Normandie | 3,243,885 | 78·9% | 2,455 | 0·08% | 379 | 0·01% |
| Pays de la Loire | 3,767,317 | 91·6% | 2,319 | 0·06% | 359 | 0·01% |
| Bretagne | 3,302,556 | 80·3% | 1,289 | 0·04% | 212 | 0·01% |
| Corse | 248,255 | 6·0% | 193 | 0·08% | 27 | 0·01% |
| Guadeloupe | 375,670 | 9·1% | 122 | 0·03% | 23 | 0·01% |
| Martinique | 350,992 | 8·5% | 148 | 0·04% | 16 | 0·00% |
| Guyane | 190,720 | 4,6% | 168 | 0·09% | 8 | 0·00% |
| La Réunion | 876,870 | 21·3% | 157 | 0·02% | 3 | 0·00% |
| Mayotte | 101,513 | 2·5% | 161 | 0·16% | 13 | 0·01% |
| Unknown | 74,799 | 1·8% | 39 | 0·05% | 3 | 0·00% |
| Social deprivation index (quintiles) - no (%) | ||||||
| 1 (the least deprivation) | 12,950,270 | 19·6% | 20,893 | 0·16% | 3,847 | 0·03% |
| 2 | 12,768,656 | 19·3% | 14,699 | 0·12% | 2,536 | 0·02% |
| 3 | 12,690,988 | 19·2% | 14,375 | 0·11% | 2,451 | 0·02% |
| 4 | 12,498,209 | 18·9% | 15,117 | 0·12% | 2,814 | 0·02% |
| 5 (the most deprivation) | 12,277,322 | 18·6% | 20,860 | 0·17% | 3,734 | 0·03% |
| Unknown | 2,865,145 | 4·3% | 1,865 | 0·07% | 279 | 0·01% |
| Lifestyle habits | ||||||
| Smoking - no (%) | 2,343,597 | 3·5% | 3,995 | 0·17% | 799 | 0·03% |
| Alcoholism - no (%) | 871,686 | 1·3% | 1,768 | 0·20% | 319 | 0·04% |
| Opioide addiction - no (%) | 208,109 | 0·3% | 308 | 0·15% | 18 | 0·01% |
| Comorbidities* - no (%) | ||||||
| Cardiometabolic | ||||||
| Obesity | 875,385 | 1·3% | 2,461 | 0·28% | 296 | 0·03% |
| Diabetes | 3,806,155 | 5·8% | 19,231 | 0·51% | 4,798 | 0·13% |
| Dyslipidemia and lipid-lowering treatments | 6,711,385 | 10·2% | 23,617 | 0·35% | 5,679 | 0·08% |
| Hereditary metabolic diseases or amyloidosis | 113,702 | 0·2% | 317 | 0·28% | 82 | 0·07% |
| Hypertension | 11,942,507 | 18·1% | 43,544 | 0·36% | 10,716 | 0·09% |
| Coronary diseases | 1,954,933 | 3·0% | 10,678 | 0·55% | 3,124 | 0·16% |
| Obliterating arterial disease of the lower limb | 643,753 | 1·0% | 4,231 | 0·66% | 1,395 | 0·22% |
| Cardiac rhythm or conduction disturbances | 2,273,991 | 3·4% | 16,254 | 0·71% | 5,210 | 0·23% |
| Heart failure | 694,978 | 1·1% | 7,578 | 1·09% | 2,613 | 0·38% |
| Valvular diseases | 645,480 | 1·0% | 4,802 | 0·74% | 1,593 | 0·25% |
| Stroke | 855,651 | 1·3% | 5,626 | 0·66% | 1,748 | 0·20% |
| Respiratory | ||||||
| Chronic respiratory diseases (excluding cystic fibrosis) | 3,522,735 | 5·3% | 12,789 | 0·36% | 3,064 | 0·09% |
| Cystic fibrosis | 8,584 | 0·0% | 32 | 0·37% | 6 | 0·07% |
| Pulmonary embolism | 149,031 | 0·2% | 1,065 | 0·71% | 309 | 0·21% |
| Cancer | ||||||
| Female breast cancer (active) | 211,500 | 0·3% | 630 | 0·30% | 142 | 0·07% |
| Female breast cancer (under surveillance) | 477,360 | 0·7% | 1,250 | 0·26% | 284 | 0·06% |
| Colorectal cancer (active) | 127,752 | 0·2% | 615 | 0·48% | 167 | 0·13% |
| Colorectal cancer (under surveillance) | 207,976 | 0·3% | 898 | 0·43% | 250 | 0·12% |
| Lung cancer (active) | 66,785 | 0·1% | 621 | 0·93% | 223 | 0·33% |
| Lung cancer (under surveillance) | 49,399 | 0·1% | 301 | 0·61% | 100 | 0·20% |
| Prostate cancer (active) | 202,266 | 0·3% | 1,029 | 0·51% | 337 | 0·17% |
| Prostate cancer (under surveillance) | 297,872 | 0·5% | 1,424 | 0·48% | 445 | 0·15% |
| Other cancers (active) | 713,122 | 1·1% | 3,944 | 0·55% | 1,240 | 0·17% |
| Other cancers (under surveillance) | 885,598 | 1·3% | 3,451 | 0·39% | 963 | 0·11% |
| Inflammatoy and skin diseases | ||||||
| Chronic inflammatory bowel diseases | 268,185 | 0·4% | 600 | 0·22% | 78 | 0·03% |
| Rheumatoid arthritis and related diseases | 287,753 | 0·4% | 1,172 | 0·41% | 268 | 0·09% |
| Ankylosing spondylitis and related diseases | 222,067 | 0·3% | 569 | 0·26% | 90 | 0·04% |
| Psoriasis | 297,025 | 0·4% | 787 | 0·26% | 142 | 0·05% |
| Psychological and neurodegenerative diseases | ||||||
| Neurotic and Mood Disorders, use of antidepressant treatments | 4,264,936 | 6·5% | 14,574 | 0·34% | 3,402 | 0·08% |
| Psychotics disorders, use of neuroleptics treatments | 762,620 | 1·2% | 3,384 | 0·44% | 940 | 0·12% |
| Psychiatric disorders starting in childhood | 165,622 | 0·3% | 146 | 0·09% | 25 | 0·02% |
| Down syndrom | 33,541 | 0·1% | 208 | 0·62% | 48 | 0·14% |
| Epilepsy | 321,047 | 0·5% | 1,302 | 0·41% | 292 | 0·09% |
| Multiple sclerosis | 113,064 | 0·2% | 324 | 0·29% | 58 | 0·05% |
| Paraplegia | 91,416 | 0·1% | 463 | 0·51% | 103 | 0·11% |
| Myopathy or myasthenia gravis | 46,191 | 0·1% | 153 | 0·33% | 41 | 0·09% |
| Parkinson disease | 244,730 | 0·4% | 1,934 | 0·79% | 645 | 0·26% |
| Dementias (including Alzheimer's disease) | 610,320 | 0·9% | 7,850 | 1·29% | 2,819 | 0·46% |
| Mental impairment | 126,180 | 0·2% | 583 | 0·46% | 120 | 0·10% |
| Other pathologies | ||||||
| Hemophilia or severe hemostasis disorders | 49,786 | 0·1% | 167 | 0·34% | 39 | 0·08% |
| HIV infection | 146,204 | 0·2% | 575 | 0·39% | 64 | 0·04% |
| Liver diseases | 397,282 | 0·6% | 2,170 | 0·55% | 487 | 0·12% |
| Chronic dialysis | 45,924 | 0·1% | 1,099 | 2·39% | 342 | 0·74% |
| Renal transplant | 42,525 | 0·1% | 547 | 1·29% | 137 | 0·32% |
| Cardiac translant | 1,669 | 0·0% | 22 | 1·32% | 4 | 0·24% |
| Liver transplant | 5,021 | 0·0% | 27 | 0·54% | 4 | 0·08% |
| Lung transplant | 1,345 | 0·0% | 25 | 1·86% | 6 | 0·45% |