Figure 5. The performance of the multitask network for translating induced pluripotent stem cell-derived cardiomyocyte (iPSC-CM) action potentials (APs) into adult cardiomyocyte (adult-CM) APs.

(A) The iPSC-CM APs used for training the multitask network contained a variety of drug-free and drugged action potential morphologies (training set). (B) Comparison between simulated (red) and translated adult-CM APs (cyan) in the training set. (C) Comparison between the histogram distribution of APD₉₀ values for simulated and translated adult-CM APs in the training set. (D) Dedicated iPSC-CM APs for testing the performance of the multitask network (test set). (E) Comparison between simulated (red) and translated adult-CM APs (cyan) in the test set. (F) Comparison between histogram distribution of APD₉₀ values for simulated and translated adult-CM APs in the test set.