Table 1.
Antibody Conjugate | Payload | Description |
---|---|---|
Antibody-toxin conjugates | Toxin | Commonly referred to as immunotoxin in the cancer immunotherapy field, ATC is characterized by the conjugation of toxins usually derived from plants or bacteria. |
Antibody-radionuclide conjugates | Radionuclide | Antibody-radionuclide conjugate is the conjugation of a radionuclide to an antibody carrier |
Antibody-drug conjugates | Small molecule or compounds | Antibody-drug conjugate is the conjugation of small molecule drugs to antibodies. |
Antibody-oligonucleotide conjugates | Oligonucleotides such as siRNA | Conjugation of oligonucleotide-based payloads such as siRNA |
Antibody-photosensitizer | Photosensitizers | Antibody-photosensitizer conjugates, also known as photoimmunotherapy (PIT), is a targeted photodynamic therapy designed with a conjugated photosensitizer to a mAb. |