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. 2021 Jul 1;12:708806. doi: 10.3389/fimmu.2021.708806

Table 1.

Antibody conjugate categories.

Antibody Conjugate Payload Description
Antibody-toxin conjugates Toxin Commonly referred to as immunotoxin in the cancer immunotherapy field, ATC is characterized by the conjugation of toxins usually derived from plants or bacteria.
Antibody-radionuclide conjugates Radionuclide Antibody-radionuclide conjugate is the conjugation of a radionuclide to an antibody carrier
Antibody-drug conjugates Small molecule or compounds Antibody-drug conjugate is the conjugation of small molecule drugs to antibodies.
Antibody-oligonucleotide conjugates Oligonucleotides such as siRNA Conjugation of oligonucleotide-based payloads such as siRNA
Antibody-photosensitizer Photosensitizers Antibody-photosensitizer conjugates, also known as photoimmunotherapy (PIT), is a targeted photodynamic therapy designed with a conjugated photosensitizer to a mAb.