Table 4.
Neurospecific protein distribution (μg/100 mg of tissue) in cerebellum and hippocampus.
Protein, brain area | Group | p value | ||||
---|---|---|---|---|---|---|
H | P | L | P vs. H | L vs. H | L vs. P | |
sNCAM, cerebellum | 0.52 ± 0.13 | 0.31 ± 0.11 | 0.46 ± 0.17 | 0.049 | 0.684 | 0.188 |
sNCAM, hippocampus | 0.40 ± 0.07 | 0.59 ± 0.15 | 0.61 ± 0.08 | 0.014 | 0.008 | 0.962 |
sGFAP, cerebellum | 20.48 ± 1.84 | 18.57 ± 0.68 | 19.19 ± 0.96 | 0.030 | 0.169 | 0.615 |
sGFAP, hippocampus | 16.46 ± 0.98 | 13.33 ± 0.84 | 13.83 ± 2.21 | 0.004 | 0.015 | 0.809 |
fGFAP, cerebellum | 134.70 ± 11.01 | 155.9 ± 10.75 | 136.00 ± 3.46 | 0.012 | 0.969 | 0.018 |
fGFAP, hippocampus | 142.90 ± 14.57 | 84.57 ± 11.18 | 156.10 ± 14.27 | <0.001 | 0.208 | <0.001 |
sNCAM: soluble neural cell adhesion molecule; sGFAP: soluble glial fibrillary acidic protein; fGFAP: filamentous glial fibrillary acidic protein; H: healthy pigs+PAF; P: EPI pigs+PAF enriched with enteric-coated pig pancreatic enzymes; L: EPI pigs+PAF predigested with microbial lipase. Data are presented as the mean ± SD.