Table 1.
Baseline characteristics of the study participants.
| Variables | Total (n = 116,855) | Impaired glucose tolerance | Diabetes mellitus | ||||
|---|---|---|---|---|---|---|---|
| Nonimpaired glucose tolerance (n = 107,028) | Impaired glucose tolerance (n = 9773) |
P
value |
Nondiabetes (n = 114,682) | Diabetes (n = 2173) |
P
value |
||
| Age (year), mean ± SD | 44.1 ± 12.9 | 43.2 ± 12.5 | 54.2 ± 13.0 | <0.001 | 43.9± 12.8 | 55.7 ± 12.6 | <0.001 |
| Gender, n (%) | |||||||
| Male | 62,868 (53.8) | 56,332 (52.6) | 6536 (66.9) | <0.001 | 61,289 (53.4) | 1579 (72.7) | <0.001 |
| Female | 53,987 (46.2) | 50,750 (47.4) | 3237 (33.1) | 53,393 (46.6) | 594 (27.3) | ||
|
| |||||||
| Height (cm), mean ± SD | 166.3 ± 8.3 | 166.3 ± 8.3 | 166.5 ± 8.5 | 0.124 | 166.3 ± 8.3 | 166.9 ± 8.5 | <0.001 |
| Weight (kg), mean ± SD | 64.9 ± 12.1 | 64.3 ± 11.9 | 70.8 ± 12.5 | <0.001 | 64.7 ± 12.0 | 73.5 ± 13.0 | <0.001 |
| BMI (kg/m2), mean ± SD | 23.3 ± 3.3 | 23.2 ± 3.2 | 25.4 ± 3.3 | <0.001 | 23.3 ± 3.3 | 26.3 ± 3.4 | <0.001 |
| FPG (mmol/L), mean ± SD | 4.9 ± 0.6 | 4.9 ± 0.6 | 5.7 ± 0.7 | <0.001 | 4.9 ± 0.6 | 6.0 ± 0.7 | <0.001 |
| HBP, n (%) | |||||||
| No | 99312 (85.0) | 92921 (86.8) | 6391 (65.4) | <0.001 | 97999 (85.5) | 1325 (61) | <0.001 |
| Yes | 17525 (15.0) | 14146 (13.2) | 3379 (34.6) | 16683 (14.5) | 848 (39) | ||
|
| |||||||
| Smoking, n (%) | |||||||
| Current smoker | 6672 (20.4) | 5878 (19.5) | 794 (30.6) | <0.001 | 19,349 (16.9) | 753 (34.7) | <0.001 |
| Ever smoker | 1328 (4.1) | 1190 (4) | 138 (5.3) | 3912 (3.4) | 123 (5.7) | ||
| Never smoker | 24,686 (75.5) | 23,022 (76.5) | 1664 (64.1) | 91,421 (79.7) | 1297 (59.7) | ||
|
| |||||||
| Drinking, n (%) | |||||||
| Current drinker | 878 (2.7) | 766 (2.5) | 112 (4.3) | 0.013 | 2374 (2.1) | 89 (4.1) | <0.001 |
| Ever drinker | 5535 (16.9) | 5069 (16.8) | 466 (18) | 16,371 (14.3) | 411 (18.9) | ||
| Never drinker | 26,273 (80.4) | 24,255 (80.6) | 2018 (77.7) | 95,937 (83.7) | 1673 (77) | ||
|
| |||||||
| Cholesterol (mmol/L), median (IQR) | 4.7 (4.2, 5.3) | 4.7 (4.1, 5.3) | 5.0 (4.4, 5.6) | <0.001 | 4.7 (4.2, 5.3) | 5.0 (4.4, 5.7) | <0.001 |
| Triglyceride (mmol/L), median (IQR) | 1.1 (0.8, 1.7) | 1.1 (0.7, 1.6) | 1.6 (1.1, 2.3) | <0.001 | 1.1 (0.8, 1.6) | 1.8 (1.2, 2.6) | <0.001 |
| HDL (mmol/L), median (IQR) | 1.4 (1.2, 1.6) | 1.4 (1.2, 1.6) | 1.3 (1.1, 1.5) | <0.001 | 1.4 (1.2, 1.6) | 1.3 (1.1, 1.5) | <0.001 |
| LDL (mmol/L), median (IQR) | 2.7 (2.3, 3.2) | 2.7 (2.3, 3.1) | 2.8 (2.4, 3.3) | <0.001 | 2.7 (2.3, 3.2) | 2.8 (2.4, 3.3) | <0.001 |
| ALT (U/L), median (IQR) | 18.0 (13.0, 27.5) | 18.0 (12.9, 27.0) | 23.0 (16.2, 35.0) | <0.001 | 18.0 (13.0, 27.1) | 26.0 (18.1, 41.0) | <0.001 |
| AST (U/L), median (IQR) | 22.0 (18.7, 26.9) | 22.0 (18.4, 26.2) | 24.0 (20.0, 29.2) | <0.001 | 22.0 (18.7, 26.8) | 25.0 (21.0, 32.0) | <0.001 |
| CCR (umol/L), median (IQR) | 69.6 (58.0, 81.2) | 69.1 (57.7, 81.0) | 73.0 (62.0, 83.5) | <0.001 | 69.3 (57.9, 81.0) | 73.4 (63.0, 82.9) | <0.001 |
| TG/HDL, median (IQR) | 0.8 (0.5, 1.3) | 0.8 (0.5, 1.3) | 1.2 (0.8, 1.9) | <0.001 | 0.8 (0.5, 1.3) | 1.4 (0.9, 2.2) | <0.001 |
| BUN (mmol/L), median (IQR) | 4.6 (3.8, 5.4) | 4.5 (3.8, 5.3) | 4.9 (4.1, 5.7) | <0.001 | 4.6 (3.8, 5.4) | 4.9 (4.1, 5.8) | <0.001 |
BMI: body mass index; FPG: fasting blood glucose; HDL: high-density lipoprotein; LDL: low-density lipoprotein; ALT: alanine aminotransferase; AST: aspartate transaminase; CCR: creatinine clearance rate; BUN: blood urea nitrogen.