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The top 10 hub genes ranked with different algorithms.
| Category | Rank method in CytoHubba | ||||
|---|---|---|---|---|---|
| MCC | MNC | Degree | EPC | Closeness | |
| Gene symbol top 10 | CHRNA4 | CHRNA4 | CHRNA4 | CHRNA4 | EGFR |
| DRD2 | EGFR | EGFR | ACHE | ACHE | |
| HTR1A | ACHE | ACHE | SLC6A4 | CHRNA4 | |
| DRD3 | SLC6A3 | SLC6A4 | SLC6A3 | PIK3CA | |
| ACHE | SLC6A4 | SLC6A3 | HTR1A | SLC6A4 | |
| SLC18A2 | PIK3CA | PIK3CA | DRD2 | DRD2 | |
| OPRM1 | DRD2 | DRD2 | SLC18A2 | PTGS2 | |
| SLC6A3 | HTR1A | HTR1A | MAOB | SLC6A3 | |
| SLC6A4 | SLC18A2 | SLC18A2 | EGFR | HTR1A | |
| MAOB | OPRM1 | OPRM1 | OPRM1 | OPRM1 | |
