. Author manuscript; available in PMC: 2021 Jul 15.

Published in final edited form as: Lancet Diabetes Endocrinol. 2017 Jan 6;5(3):165–173. doi: 10.1016/S2213-8587(16)30315-1

Table 4.

Laboratory values by study visit.

	Baseline	Long-term Follow-Up
Fasting Insulin (uU/mL), n	53	48
Observed, mean (SD)	37.8 (20.03)	8.3 (7.30)
Model-estimated^a, mean (95% CI)	37.6 (32.2,43.1)	7.0 (5.6,8.5)

Fasting Glucose (mmol/L), n	49	48
Observed, mean (SD)	5.37 (0.94)	4.76 (1.97)
Model-estimated^a, mean (95% CI)	5.37 (5.11, 5.65)	4.75 (4.17, 5.34)

HbA1c (%), n	31	50
Observed, mean (SD)	5.3 (0.65)	5.2 (1.30)
Model-estimated^a, mean (95% CI)	5.3 (5.1.5.6)	5.2 (4.9,5.6)

HOMA-IR, n	48	45
Observed, mean (SD)	9.0 (5.68)	1.5 (1.25)
Model-estimated^a, mean (95% CI)	9.2 (7.6,10.9)	1.5 (1.1,1.9)

Fasting Triglycerides (mmol/L), n	50	45
Observed, Median (Q1,Q3)	1.43 (1.12, 2.05)	0.86 (0.68, 1.39)
Model-estimated^a, mean (95% CI)	1.45 (1.27, 1.66)	0.99 (0.86, 1.13)

LDL (mmol/L), n	50	50
Observed, mean (SD)	2.78 (0.68)	2.44 (0.79)
Model-estimated^a, mean (95% CI)	2.78 (2.59, 2.97)	2.44 (2.22, 2.67)

HDL (mmol/L), n	50	50
Observed, mean (SD)	0.91 (0.19)	1.46 (0.45)
Model-estimated^a, mean (95% CI)	0.91 (0.86, 0.96)	1.45 (1.32, 1.58)

Linear mixed models were used to calculate the modeled results.