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. 2021 Jun 24;16(7):1735–1748. doi: 10.1016/j.stemcr.2021.05.018

Figure 6.

Figure 6

Macrophage infection by HIV-1 or Zika virus under different culture conditions

(A) Percentage of macrophages infected with a GFP-encoding, single-round HIV-1 pseudotyped virus measured by flow cytometry.

(B) CD4, CCR5, and CXCR4 surface expression measured by flow cytometry shown as ratio of geometric MFI to the isotype control.

(C) MR1766 Zika virus titer from infected macrophages shown in plaque-forming units (pfu)/mL.

Significance was calculated by (A) two-way ANOVA, Sidak’s multiple comparison test, (B) Wilcoxon matched-pairs signed rank t test. (A–C) Mean ± SD n = 4 experiments in each of 2 independent donors’ cell lines. Significance is shown when p < 0.05, ∗∗ p < 0.01, ∗∗∗ p < 0.001.