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. 2021 Jul 15;6:60. doi: 10.1038/s41525-021-00227-3

Fig. 5. The number of candidate variants that follow different inheritance modes per genome using two different variant callers.

Fig. 5

A Only “impactful” variants as determined by slivar using annotations from VEP, snpEff, or bcftools are shown. B The set of variants is extended to include synonymous, UTR, and conserved intron regions (but not all intronic). Counts for autosomal dominant variants are shown in a separate plot due to the much larger numbers. Each dot represents the number of candidate variants (y-axis) passing the inheritance mode (x-axis), genotype-quality, population allele-frequency, and allele-balance filters for a single family. Gray bars indicate the mean number for each class and inheritance mode. We show Fig. 5A for the sarcoma replication cohort in Supplementary Fig. 14.