Table 2.

Mean number of candidate variants for each inheritance mode for a cohort of 149 whole-exome trios and and a cohort of 94 whole-genome trios.

Inheritance mode	Exome GATK	Genome GATK	Genome DeepVariant	Exome GATK impactful	Genome GATK (impactful)	Genome DeepVariant (impactful)	Genome GATK (genic except intronic)
De novo	1.4	434.7	178.7	1.1	3.5	1.4	13.9
Autosomal recessive	0.5	185.0	320.7	0.4	0.7	0.8	5.3
Compound heterozygote	7.3	21.9	21.9	3.4	11.2	9.2	25.0
X-linked recessive	0.3	572.7	401.8	0.3	2.9	1.7	18.0
X-linked de novo	0.3	5.0	2.5	0.3	0.0	0.0	0.2
Autosomal dominant	102.0	10,874.1	11704.6	68.9	112.9	99.0	653.2