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. 2021 Jul 15;7:58. doi: 10.1038/s41531-021-00207-5

Table 2.

Factors associated with the number of NMS in patients with PD.

Unadjusted model Adjusted model
B 95%CI P-value B 95%CI P-value
Female sex 0.153 0.037–0.628 0.009* 0.416 0.110–1.571 0.196
Age 1.145 1.074–1.221 <0.001* 1.112 1.044–1.184 0.001*
Disease duration 1.573 1.007–2.458 0.047* 1.078 0.684–1.698 0.746
Education 0.971 0.818–1.154 0.741 1.045 0.891–1.225 0.588
LEDD 1.005 1.002–1.008 0.001* 1.002 0.998–1.006 0.360
Use of levodopa 10.912 1.768–67.357 0.010* 2.024 0.213–19.242 0.539
Use of dopamine receptor 1.636 0.275–9.755 0.589 0.421 0.066–2.676 0.359
Use of antidepressant 3.087 0.214–44.556 0.408 2.682 0.235–30.662 0.427
UPDRS III 1.172 1.097–1.251 <0.001* 1.124 1.053–1.201 <0.001*

*Significant difference.

NMS non-motor symptoms, PD parkinson’s disease, LEDD levodopa equivalent daily dose, UPDRS unified parkinson’s disease rating scale.