Table 3.

Association between baseline NMS number and motor progression in PD.

	Number of NMS at baseline
	OR (95%CI)	P-value
UPDRS-III 3-point increase from baseline to 1-year	1.074 (1.013–1.139)	0.017*
UPDRS-III 6-point increase from baseline to 2-year	1.113 (1.048–1.182)	0.001*
UPDRS-III 9-point increase from baseline to 3-year	1.117 (1.048–1.191)	<0.001*

* Significant difference.

In the multivariate models, sex, age at enrollment, age of onset, disease duration, and UPDRS III score at baseline were adjusted.

PD parkinson’s disease, NMS non-motor symptom, UPDRS unified Parkinson’s disease rating scale.