Skip to main content
. 2021 Jul 15;11:14546. doi: 10.1038/s41598-021-93868-4

Table 2.

Description of all found associations between trans-nonachlor and adiposity measures.

Publication characteristics Adiposity
BMI (kg/m2) Fat mass WC (cm) VAT/SAT
References Sex. Age group Subjects Exposure Contrast # Estimate (95% CI) Estimate (95% CI) Estimate (95% CI) Estimate (95% CI)
Pelletier et al.20 ♂ (36–58) μg/Kg lipids ρ = 0.34 (p = 0.02) ρ = 0.23 (p = 0.143)
Magnusdottiret al.21 ♂ (37 ± 5.4)* ng/g lipid ρ = 0.18 (p = 0.12)
Hue et al.22 ♂ † μg/kg lipids r = 0.28 (p = 0.07)
Lee et al.25 ♂♀ (≥ 20)

ng/g lipid

 ≥ 90th vs. BDL

ρ = 0.03 (p > 0.01) ρ = 0.01 (p > 0.01)
Lee et al.27 ♂♀ (≥ 20)  > 75th vs. BDL OR = 1.4 (0.7; 2.9)
Cho et al.23 ♂ (< 50) ng/g lipids

r = 0.01

(p > 0.05)

Cho et al.23 ♂ (≥ 50) ng/g lipids

r = 0.11

(p < 0.01)

Cho et al.23 ♀ (< 50) ng/g lipids r = − 0.13 (p < 0.001)
Cho et al.23 ♀ (≥ 50) ng/g lipids

r = 0.04

(p > 0.05)

Ronn et al.24 ♂♀ (70y.o.)

Per 1-unit

(ln ng/g lipid)

β = 1.86 (0.85; 2.86)
Lee et al.29 ♂ (70y.o.) 370–4252 vs. < 173 (pg/ml) OR = 2.5 (1.1; 5.6)
Lee et al.29 ♀ (70y.o.) 370–4252 vs. < 173 (pg/ml) OR = 0.9 (0.5; 1.8)
Lee et al.29 ♂ (≥ 75) 370–4252 vs. < 173 (pg/ml) OR = 0.7 (0.2; 2.4)
Lee et al.29 ♀ (≥ 75) 370–4252 vs. < 173 (pg/ml) OR = 0.7 (0.2; 1.9)
Roos et al.31 ♂♀ (70y.o.)

Per 1-unit

(ln ng/g lipid)

VAT: β = 17.0

(4.7; 30.0)

SAT: β = 19.0

(− 2.6; 40.0)

Jaacks et al.41 ♀ (18–40) ng/mL ρ = 0.07 (p = 0.27)
Lauritzen et al.47

♀ (18–41)

Pregnant

Per 1-unit

(ln ng/g lipid)

# β = − 2.0 (− .4; − 0.6)
Bjerregaard-Olesen et al.40

♀ (26–32)

Pregnant

μg/kg lipids

# β = − 0.02

(− 0.04; 0.00)

Rosenbaum et al.39 ♂♀ (53.6 ± 16.2) pg/g wet weight ρ = − 0.129
Kim et al.37 ♂♀ (41–69) ng/g lipid

r = 0.16

(p < 0.05)

Chen et al.45

♀ (19–40)

Pregnant

ng/g lipid # OR = 1.19 (0.42; 3.33)
Meta-analysis β = 0.02 (− 0.01; 0.06)

BMI, Body Mass Index; WC, Waist Circumference;VAT, Visceral adipose tissue, SAT Subcutaneous adipose tissue; β, Beta coefficient; OR, Odds Ratio; ρ, spearmen correlation; r, Pearson correlation; * Mean; †, Without information; # Pre pregnancy-BMI as outcome; italic values represents studies for which was possible to perform a meta-analysis plot.