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. 2021 Jul 15;12:4340. doi: 10.1038/s41467-021-24666-9

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 3 — a, b Images of a single microglia cell in mouse hippocampal tissue acquired before correction (m = 0), after the first iteration (m = 1120), and after convergence of the DASH and F-SHARP algorithms (m = 10,120), respectively, with the resulting correction masks shown in the inset and scale bar corresponding to 10 μm. Similar results were reproduced five times. c Profiles along the gray, dashed line in part a for no correction (black), DASH correction (blue), and F-SHARP correction (red).