. Author manuscript; available in PMC: 2021 Aug 1.

Published in final edited form as: Lupus. 2021 May 14;30(9):1394–1404. doi: 10.1177/09612033211016100

Table 2:

Clinical and histologic features of the active lupus nephritis patients:

Clinical Presentation (n=28)
- Serum creatinine, mean (SD), mg/dL	0.78 ± 0.11
- eGFR, mean (SD), ml/min/1.73m²	104.9 ± 7.2
- Protein: Creatinine ratio, mean (SD), mg/mg	3.83 ± 0.95
- Renal SLEDAI score, median (IQR)^†	10 (4–16)

Histologic features (n=22)

- Activity Index, median (IQR)^§	4 (0–17)
○ Endocapillary proliferation, N (%)	12 (54.5)
○ Glomerular WBC infiltration, N (%)	9 (40.9)
○ Hyaline deposits, N (%)	7 (31.8)
○ Karyorrhexis, N (%)	5 (22.7)
○ Cellular crescents, N (%)	5 (22.7)
○ Interstitial inflammation, N (%)	9 (40.9)
- Chronicity Index, median (IQR)	0 (0–3)
○ Glomerulosclerosis, N (%)	6 (27.3)
○ Fibrous crescents, N (%)	0
○ Tubular atrophy and interstitial fibrosis, N (%)	7 (31.8)

eGFR: estimated glomerular filtration rate; IQR: Interquartile range SLEDAI: Systemic Lupus

Erythematosus Disease Activity Index

^†:

Range 0–16; 0 = inactive LN

^§:

Range 0–24; 0 = no LN activity features

^¶:

Range 0–12; 0 = no LN chronic changes