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. Author manuscript; available in PMC: 2021 Aug 1.
Published in final edited form as: Lupus. 2021 May 14;30(9):1394–1404. doi: 10.1177/09612033211016100

Table 3:

Plasma biomarker levels and conventional laboratory measures differentiating active lupus nephritis*

Active renal SLE (n=28) Active non-renal SLE (n=29) Inactive SLE (n=26) Healthy controls (n=25) P-values
Axl (pg/ml) 3765 ± 235.3 2825 ± 200.7 2513 ± 130.0 2091 ± 152.6 <0.0001 §
0.002
0.04
Ferritin (ng/ml) 110.8 ± 25.50 31.2 ± 3.39 18.3 ± 3.96 15.1 ± 2.70 <0.0001 §
<0.0001
>0.999
IGFBP4 (ng/ml) 180146 ± 355 140049 ± 320 108548 ± 247 157269 ± 411 0.51 §
0.21
>0.99
sTNFR2
(pg/ml)
6966 ± 571 7195 ± 1002 5800 ± 568 6040 ± 1163 0.03 §
0.18
>0.999
dsDNA
Ab (titer)
80 (0–1280) 40 (0–160) 0 (0–17.5) ________ 0.02 §
0.003
0.16
C3
(mg/dL)
61.7 ± 7.5 87.2 ± 5.4 113.5 ± 4.5 ________ <0.0001 §
<0.0001
0.09
*

Values were expressed as mean± standard deviation, except for dsDNA antibody titers (median, interquartile range)

§:

P-value for comparison between all groups

†:

P-value for active SLE vs. inactive SLE patients

¶:

P-value for active renal vs. active non-renal SLE patients