Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Jul 15;11:14511. doi: 10.1038/s41598-021-93861-x

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2021, corrected publication 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

The performance of rats in three groups in the Morris water maze test. (A) Typical behavioral traces of three groups rats in the place navigation test. The more lines in the quadrants, the longer the escape latency. The rats in the CLP sepsis model group had significantly (P = 0.001) longer escape latency compared with the Sham and CLP + vitamin C groups. (B) Typical behavioral traces of the rats in three groups in the spatial probe test. The denser the blue lines in the quadrant where the platform is, the longer the retention time of rats. The rat retention time was significantly (P = 0.001) elongated in the platform quadrant in the Sham and CLP + vitamin C group compared with the CLP sepsis model group. (C) Comparison of the escape latency of the rats in three groups. The escape latency was significantly (P = 0.003) improved in the CLP + vitamin C group compared with the CLP model group. D&E. Comparison of the crossing frequency (D) and time (E) spent in the target quadrant of the rats in three groups, with significant improvement in the CLP + vitamin C group compared with CLP group. *P < 0.05 and **P < 0.01 compared with sham group; ^#P < 0.05 compared with CLP + saline group. CLP cecal ligation and puncture, Vit C vitamin C.