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. 2021 Jul 15;11:14511. doi: 10.1038/s41598-021-93861-x

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© The Author(s) 2021, corrected publication 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Experimental design. Twenty-four hours after CLP-induced sepsis model was established, inflammatory factors, oxidative stress of Serum and hippocampus, BBB permeability, Nissl's staining of hippocampus, and Western blot of hippocampus were evaluated. Ten days after CLP-induced sepsis model, behavioral tests of rats were performed.