Fig. 2. Scope of N-heterocyclic substrates.

Reaction conditions: N-heterocyclic substrates (0.2 mmol), H₂O (0.6 mmol), CuOAc (0.02 mmol), ligand (0.024 mmol), NFSI (0.3 mmol), CH₃CN (2.0 mL), under N₂; isolated yields reported. ^aL1, temperature: 35 °C. ^bL1, ROH (0.6 mmol). ^cL2, temperature: 20 °C. ^dLigand L2, temperature: 30 °C. ^eL6, Selectflour II instead of NFSI, temperature: 20 °C. ^fCuOAc (0.2 eq.), L6 (0.22 eq), Selectflour II (2.0 eq.) instead of NFSI, temperature: 20 °C.