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. Author manuscript; available in PMC: 2022 Aug 1.
Published in final edited form as: Drug Alcohol Depend. 2021 May 21;225:108756. doi: 10.1016/j.drugalcdep.2021.108756

Table 4.

Evaluating education, gender, and race as effect modifiers of the relationship between conditions and any cigarette-free days and number of cigarette free days during the 20 week study period (n=1001)

Immediate nicotine reduction versus gradual reduction Immediate nicotine reduction versus no reduction (control)
Any cigarette free days Number of cigarette free days Any cigarette free days Number of cigarette free days
Odds Ratio
(95% CI)		 IRR
(95% CI)		 Odds Ratio
(95% CI)		 IRR
(95% CI)
p-value p-value p-value p-value
>HS*Treat† >HS*Treat† >HS*Treat† >HS*Treat†
0.77
(0.42, 1.41)		 1.08
(0.45, 2.60)		 0.64
(0.30, 1.38)		 0.86
(0.28, 2.64)
p=0.398 p=0.866 p=0.257 p=0.794
Male*Treat† Male*Treat† Male*Treat† Male*Treat†
0.86a
(0.48, 1.54)		 1.01b
(0.44, 2.28)		 0.92
(0.44, 1.94)		 0.93
(0.30, 2.90)
p=0.600 p=0.989 p=0.824 p=0.895
White*Treat† White*Treat† White*Treat† White*Treat†
1.04
(0.55, 1.97)		 2.98
(1.14, 7.75)		 1.13
(0.50, 2.60)		 1.18
(0.33, 4.24)
p=0.913 p=0.025 p=0.766 p=0.797
a

Interpretation: When less than one, the moderator category shown (e.g., Male) has a lower odds and when greater than one, the moderator category shown has a greater odds than the reference moderator category (e.g., females) of having any cigarette-free day in the immediate versus gradual or control condition.

b

Interpretation: Ratio of the rate of cigarette-free day for immediate relative to gradual or control condition in the moderator category shown (e.g., male) compared to the reference moderator category (e.g., female). HS; high school

Education models are adjusted for site, employment, baseline FTND, baseline NMR, gender, race, menthol smoking, and urinary TNE at baseline (adjusted for creatinine); Gender models are adjusted for site, employment, baseline FTND, baseline NMR, age education, CPD at baseline, smoking duration, menthol smoking, CO at baseline, Urinary TNE at baseline (adjusted for creatinine); Race models are adjusted for site, employment, baseline FTND, baseline NMR, age education, CPD at baseline, menthol smoking, CO at baseline, Urinary TNE at baseline (adjusted for creatinine)