. Author manuscript; available in PMC: 2022 Sep 1.

Published in final edited form as: J Affect Disord. 2021 Jun 7;292:500–507. doi: 10.1016/j.jad.2021.05.107

Table 3:

Effects of depression status, alcohol consumption and medications on Bray-Curtis dissimilarity using PERMANOVA test.

Variable	F-value	R²	p-value
Depression Status	0.92	0.011	0.51
Psychiatric Status	0.93	0.017	0.57
MDD Status	0.91	0.008	0.52
Taking SSRI	0.97	0.006	0.42
Depression Status by Taking SSRI	0.95	0.024	0.54
MDD Trajectory Group	0.81	0.023	0.79
Antibiotics use >6 months prior to study	0.71	0.004	0.76
Alcohol use	1.12	0.007	0.34

SSRI: selective serotonin reuptake inhibitor. MDD: major depressive disorder

Depression Status included participants who were never depressed (n==50), in episode (n=66), and in remission (n=44).

Psychiatric Status included participants who were healthy controls (n=27), psychiatric controls (n=23), in episode (n=66), and in remission (n=44).

MDD status was restricted to participants who were in episode (n=66) or in remission (n=44).

Trajectory group 1) participants with no depressive symptoms (n=68), 2) participants with low-level depressive symptoms (n=17), 3) participants in episode, remitting during the course of the study (n=47), and 4) participants persisting in episode during the course of the study (n=21).