Table 5.
Edgewise ROI-to-ROI connectivity analyses (including only participants pre- and post-treatment scans; n=56) showing clusters of edges with decreases in connectivity pre- to post-treatment across all participants controlling for age and sex. Results represent significant clusters among 44,850 possible connections in the Seitzman-300 ROI atlas. Numeric labels reflect the order in which ROIs appear listed in the atlas information text file (https://greenelab.wustl.edu/data_software).
| MNI Coordinates (x,y,z) | TFCE | T(54) | p-uncorrected | p-FDR | p-FWE | |
|---|---|---|---|---|---|---|
| Cluster 1/4 | 102.43 | .000001 | .003523 | .004 | ||
| UN.9 — DM.108 | (65, −24, −19) – (−3, 44, −9) | 4.48 | .00004 | .268293 | ||
| DM.89 — PM.138 | (−44, −65, 35) – (−2, −35, 31) | 4.17 | .000112 | .268293 | ||
| UN.9 — DM.119 | (65, −24, −19) – (11, −54, 17) | 4.16 | .000114 | .268293 | ||
| DM.104 — DM.99 | (−7, −55, 27) – (−11, −56, 16) | 4.16 | .000114 | .268293 | ||
| DM.97 — DM.119 | (−17, 29, 53) – (11, −54, 17) | 4.08 | .00015 | .292326 | ||
| DM.89 — DM.99 | (−44, −65, 35) – (−11, −56, 16) | 3.98 | .000209 | .315444 | ||
| DM.97 — DM.99 | (−17, 29, 53) – (−11, −56, 16) | 3.96 | .000218 | .315444 | ||
| DM.89 — DM.108 | (−44, −65, 35) – (−3, 44, −9) | 3.64 | .000602 | .404922 | ||
| DM.89 — DM.106 | (−44, −65, 35) – (−3, −49, 13) | 3.59 | .000706 | .404922 | ||
| DM.89 — DM.92 | (−44, −65, 35) – (−39, −75, 44) | 3.52 | .000892 | .44055 | ||
| DM.89 — DM.119 | (−44, −65, 35) – (11, −54, 17) | 3.4 | .00129 | .452504 | ||
| UN.9 — DM.105 | (65, −24, −19) – (−7, 51, −1) | 3.39 | .001307 | .452504 | ||
| DM.125 — DM.92 | (23, 33, 48) – (−39, −75, 44) | 3.38 | .00134 | .452504 | ||
| DM.112 — DM.106 | (6, −59, 35) – (−3, −49, 13) | 3.29 | .001759 | .476628 | ||
| UN.9 — DM.99 | (65, −24, −19) – (−11, −56, 16) | 3.24 | .002035 | .495236 | ||
| DM.97 — DM.108 | (−17, 29, 53) – (−3, 44, −9) | 3.22 | .002201 | .501351 | ||
| DM.100 — DM.92 | (−10, 39, 52) – (−39, −75, 44) | 3.21 | .002267 | .509138 | ||
| DM.93 — DM.106 | (−35, 20, 51) – (−3, −49, 13) | 3.16 | .002581 | .518822 | ||
| DM.93 — DM.108 | (−35, 20, 51) – (−3, 44, −9) | 3.11 | .003025 | .524086 | ||
| UN.9 — DM.116 | (65, −24, −19) – (8, 42, −5) | 3.09 | .003117 | .524086 | ||
| DM.115 — DM.92 | (8, −48, 31) – (−39, −75, 44) | 3.08 | .003209 | .524086 | ||
| DM.100 — DM.119 | (−10, 39, 52) – (11, −54, 17) | 3.07 | .003311 | .524086 | ||
| DM.97 — DM.92 | (−17, 29, 53) – (−39, −75, 44) | 3.07 | .003366 | .524086 | ||
| DM.104 — DM.119 | (−7, −55, 27) – (11, −54, 17) | 3.06 | .003488 | .525095 | ||
| DM.104 — DM.92 | (−7, −55, 27) – (−39, −75, 44) | 3.03 | .003796 | .529749 | ||
| DM.130 — DM.106 | (52, −59, 36) – (−3, −49, 13) | 3.02 | .003851 | .529749 | ||
| DM.104 — DM.107 | (−7, −55, 27) – (−2, −37, 44) | 3.01 | .003943 | .529749 | ||
| Cluster 2/4 | 83 | .000005 | .005213 | .026 | ||
| DM.97 — DM.116 | (−17, 29, 53) – (8, 42, −5) | 4.05 | .000167 | .311434 | ||
| Cluster 3/4 | 79.59 | .000006 | .005213 | .032 | ||
| DM.101 — DM.116 | (−10, 55, 39) – (8, 42, −5) | 3.73 | .000458 | .375425 | ||
| DM.101 — DM.122 | (−10, 55, 39) – (12, 36, 20) | 3.48 | .001009 | .452504 | ||
| Cluster 4/4 | 74.9 | .000009 | .005389 | .045 | ||
| DM.97 — DM.107 | (−17, 29, 53) – (−2, −37, 44) | 3.3 | .001704 | .476628 | ||
Note. DM – Default Mode, FDR – False Discovery Rate, FWE – Family Wise Error, PM – ParietoMedial, ROI – Region of Interest, TFCE – Threshold Free Cluster Enhancements, UN – Unassigned