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. 2021 Jul 15;12(7):706. doi: 10.1038/s41419-021-04008-9

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 6 — a The cell cycle of LK cells, LSK cells, and LT-HSCs in the Gpx4^flox/flox Vav-Cre mice after 3 weeks of a V_E-depleted diet. b The HSPCs in the Gpx4^flox/flox Vav-Cre mice after 3 weeks of a V_E-depleted diet were determined to be DAPI negative. c Left panel: representative flow cytometric plots of lipid ROS in c-kit⁺ cells of the Gpx4^flox/flox Vav-Cre mice after 3 weeks of a V_E-depleted diet. Right panel: statistical data of the relative MFI of lipid ROS. d Left panel: representative flow cytometric plots of ROS in LK cells, LSK cells, and LT-HSCs of the Gpx4^flox/flox Vav-Cre mice after 3 weeks of a V_E-depleted diet. Right panel: statistical data of the relative MFI of ROS. N = at least three mice in each group. Data are the mean ± SD. (ns not significant, *P < 0.05, **P < 0.01, ***P < 0.001).