Table 4.

Effect of CB on the mRNA expression of TLR-2, TLR-4, and TLR-5 in ETEC K88-infected piglets^a.

Item	NC	PC	PC + CB	Contrast (P-value)b
				#1	#2	#3
TLR-2, fold change
3 h	1.00 ± 0.02	2.80 ± 0.29	1.94 ± 0.15	<0.001	0.003	0.006
6 h	1.00 ± 0.06	3.69 ± 0.35	2.98 ± 0.21	<0.001	<0.001	0.014
12 h	1.00 ± 0.02	4.36 ± 0.19	3.52 ± 0.37	<0.001	<0.001	0.027
TLR-4, fold change
3 h	1.00 ± 0.04	4.71 ± 0.43	2.52 ± 0.25	<0.001	0.002	<0.001
6 h	1.00 ± 0.04	7.00 ± 0.60	3.32 ± 0.27	<0.001	0.001	<0.001
12 h	1.00 ± 0.02	9.02 ± 0.66	4.25 ± 0.40	<0.001	<0.001	<0.001
TLR-5, fold change
3 h	1.00 ± 0.05	1.96 ± 0.14	1.58 ± 0.09	<0.001	0.001	0.017
6 h	1.00 ± 0.05	2.83 ± 0.41	2.34 ± 0.23	<0.001	0.003	0.029
12 h	1.00 ± 0.03	3.57 ± 0.36	2.85 ± 0.30	<0.001	<0.001	0.013

^aNC, piglets were fed the daily diet and received oral administration of sterile physiological saline; PC, piglets were fed the daily diet and received oral challenge with ETEC K88; PC + CB, piglets were fed the CB-supplemented diet and received oral challenge with ETEC K88. Values are means ± standard error.

^bContrast, #1:NC vs. PC; #2: NC vs. PC + CB; #3: PC vs. PC + CB.