Table 5.
Effect of CB on the activation of NF-κB p65 and IκBα in ETEC K88-infected pigletsa.
Item | NC | PC | PC + CB | Contrast (P-value)b | ||
---|---|---|---|---|---|---|
#1 | #2 | #3 | ||||
p-p65, fold change | ||||||
3 h | 1.00 ± 0.06 | 1.22 ± 0.13 | 1.03 ± 0.07 | 0.113 | 0.830 | 0.164 |
6 h | 1.00 ± 0.05 | 2.05 ± 0.28 | 1.45 ± 0.17 | 0.002 | 0.116 | 0.045 |
12 h | 1.00 ± 0.04 | 1.53 ± 0.15 | 1.31 ± 0.14 | 0.007 | 0.095 | 0.208 |
p-IκBα, fold change | ||||||
3 h | 1.00 ± 0.06 | 1.31 ± 0.08 | 1.04 ± 0.07 | 0.027 | 0.717 | 0.015 |
6 h | 1.00 ± 0.07 | 2.43 ± 0.20 | 1.62 ± 0.13 | <0.001 | 0.009 | 0.001 |
12 h | 1.00 ± 0.06 | 1.39 ± 0.16 | 1.13 ± 0.05 | 0.017 | 0.394 | 0.090 |
NC, piglets were fed the daily diet and received oral administration of sterile physiological saline; PC, piglets were fed the daily diet and received oral challenge with ETEC K88; PC + CB, piglets were fed the CB-supplemented diet and received oral challenge with ETEC K88. Values are means ± standard error.
Contrast, #1:NC vs. PC; #2: NC vs. PC + CB; #3: PC vs. PC + CB.