Table 6.

Effect of CB on the mRNA expression of key proteins in TLRs/NF-κB inflammatory signaling^a.

Item	NC	PC	PC + CB	Contrast (P-value)b
				#1	#2	#3
MyD88, fold change
3 h	1.00 ± 0.04	2.76 ± 0.14	2.91 ± 0.23	<0.001	<0.001	0.509
6 h	1.00 ± 0.08	4.24 ± 0.32	4.81 ± 0.25	<0.001	<0.001	0.112
12 h	1.00 ± 0.08	5.52 ± 0.29	5.57 ± 0.25	<0.001	<0.001	0.886
Tollip, fold change
3 h	1.00 ± 0.06	0.28 ± 0.04	1.38 ± 0.07	<0.001	<0.001	<0.001
6 h	1.00 ± 0.07	0.42 ± 0.05	1.70 ± 0.10	<0.001	<0.001	<0.001
12 h	1.00 ± 0.07	0.52 ± 0.06	2.13 ± 0.14	0.003	<0.001	<0.001
BCl3, fold change
3 h	1.00 ± 0.06	0.90 ± 0.08	1.35 ± 0.13	0.476	0.017	0.004
6 h	1.00 ± 0.07	1.14 ± 0.09	1.95 ± 0.16	0.403	<0.001	<0.001
12 h	1.00 ± 0.04	1.29 ± 0.09	2.38 ± 0.27	0.255	<0.001	0.002

^aNC, piglets were fed the daily diet and received oral administration of sterile physiological saline; PC, piglets were fed the daily diet and received oral challenge with ETEC K88; PC + CB, piglets were fed the CB-supplemented diet and received oral challenge with ETEC K88. Values are means ± standard error.

^bContrast, #1:NC vs. PC; #2: NC vs. PC + CB; #3: PC vs. PC + CB.