Table 6.
Comparative characteristics and evaluation of antipsychotics generations and antipsychotics combinations, n (%).
| Antipsychotics combinations | Psychiatric hospital patients, n | |||
|---|---|---|---|---|
| (1) Kemerovo, 94 | (2) Tomsk, 131 | (3) Omsk, 91 | p-value | |
| Antipsychotics generations | ||||
| Conventional antipsychotics | 53 (56.4%) | 22 (16.8%) | 75 (82.4%) | p1−2 = 0.0001* |
| Atypical antipsychotics | 41 (43.6%) | 109 (83.2%) | 16 (17.6%) | p1−3 = 0.0001* |
| p2−3 = 0.0001* | ||||
| Antipsychotics combinations | ||||
| Monotherapy | 51 (54.3%) | 89 (67.9%) | 43 (50.0%) | p1−2 = 0.0186* |
| p1−3 = 0.1702 | ||||
| p2−3 = 0.001* | ||||
| Two antipsychotics combine | 33 (35.1%) | 37 (28.3%) | 43 (50.0%) | p1−2 = 0.1373 |
| p1−3 = 0.046* | ||||
| p2−3 = 0.0019* | ||||
| Three antipsychotics combine | 10 (10.6%) | 5 (3.8%) | 5 (5.4%) | p1−2 = 0.0224* |
| p1−3 = 0.096 | ||||
| p2−3 = 0.279 | ||||
*
p < 0.05, statistically significant difference; comparisons between groups were performed using the chi-squared test.