Table 9.

Predicted values of pIC₅₀ obtained by the QSAR models developed and observed pIC₅₀ for Crizotinib.

Compounds	pred (pIC50) c-Met				IC50 (nM) c-Met
	MLR	MNLR		ANN	MLR	MNLR	ANN
5	9.27	9.28		9.33	0.537	0.190	0.467
9	9.66	9.72		9.66	0.212	0.281	0.218
14	9.92	9.55		9.42	0.120	0.490	0.380
16	9.25	9.31		9.36	0.562	0.204	0.436
27	9.71	9.69		9.66	0.194	0.223	0.218
40	9.64	9.65		9.64	0.230	0.363	0.230
46	9.39	9.44		9.54	0.407	0.190	0.288
Crizotinib
Observed (pIC50 = 8.09)			Observed (IC50 =8 nM)