Table 4.
Extraction recovery and matrix effect for the analytes in human plasma.
| Analytes | Concentration (ng/mL)a | Extraction recovery |
Matrix effect |
||
|---|---|---|---|---|---|
| Mean (%) | RSD (%) | Mean (%) | RSD (%) | ||
| INH | 120 | 94.18 | 3.78 | 94.91 | 2.86 |
| 1920 | 97.20 | 2.17 | 92.39 | 3.23 | |
| 4800 | 95.94 | 3.00 | 88.23 | 4.06 | |
| AC-INH | 480 | 84.24 | 3.40 | 95.53 | 4.18 |
| 7680 | 97.41 | 2.64 | 99.66 | 3.05 | |
| 19 200 | 94.15 | 3.41 | 103.24 | 5.26 | |
| RIF | 500 | 99.59 | 9.87 | 97.36 | 4.53 |
| 8000 | 98.66 | 3.35 | 95.89 | 3.26 | |
| 20 000 | 99.91 | 3.11 | 98.05 | 2.16 | |
| EMB | 240 | 93.83 | 2.44 | 98.02 | 3.08 |
| 3840 | 93.83 | 1.19 | 99.86 | 3.71 | |
| 9600 | 93.36 | 4.53 | 94.92 | 2.58 | |
| PZA | 1200 | 97.46 | 3.33 | 97.38 | 3.42 |
| 19 200 | 98.60 | 2.49 | 98.61 | 3.58 | |
| 48 000 | 97.52 | 2.78 | 101.36 | 2.08 | |
a
The QC samples from top to bottom are the LQC, MQC, and HQC.