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. 2021 Jul 2;15:683103. doi: 10.3389/fnins.2021.683103

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Copyright © 2021 Huq, Warner, Buckhaults and Sachs.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Body weights of wild-type (WT) and knock-in (KI) mice on standard diet (SD) and high fat diet (HFD). (A) Quantification of average body weights over the time course of the experiment. (B) Calculation of the average percent gain in body weight over the course of the experiment for each group. (C) Average daily food intake (grams of chow per gram body weight) in mice consuming either SD or HFD. Results are expressed as the mean, and error bars indicate standard error. “^∗” indicates a significant main effect of diet by two-way ANOVA, p < 0.05. N = 10 per WT group and 11 per KI group.