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. 2021 Jul 2;12:637945. doi: 10.3389/fgene.2021.637945

TABLE 2.

Risk of macro- and microvascular complications in different clusters in long-term adult diabetes relative to MARD.

Complications SAID
SIDD
IROD1
IROD2
OR (95% CI) P-value OR (95% CI) P-value OR (95% CI) P-value OR (95% CI) P-value
PDR 9.32 (2.15, 40.46) 0.003* 2.42 (0.96, 6.07) 0.06 0.53 (0.16, 1.79) 0.31 0.73 (0.23, 2.32) 0.59
CKD 2.59 (1.34, 5.00) 0.005* 2.03 (1.21, 3.40) 7.1 × 10–3* 1.63 (1.08, 2.46) 0.02* 0.85 (0.53, 1.39) 0.52
Neuropathy 3.30 (1.29, 8.43) 0.01* 13.60 (5.20, 35.50) 1.0 × 10–7* 2.08 (1.28, 3.37) 3.0 × 10–3* 0.70 (0.45, 1.09) 0.12
CVD 0.61 (0.25, 1.51) 0.3 1.13 (0.60, 2.11) 0.71 1.11 (0.68, 1.8) 0.68 1.44 (0.87, 2.36) 0.15

PDR, proliferative diabetic retinopathy; CKD, chronic kidney disease; CVD, cardiovascular disease; OR, Odds Ratios; 95% CI, 95% confidence intervals; and p-values were calculated using logistic regression adjusted for sex, age, and diabetes duration. *Significant after adjustment for the multiple testing using FDR (<0.05).