TABLE 2.
Risk of macro- and microvascular complications in different clusters in long-term adult diabetes relative to MARD.
Complications | SAID |
SIDD |
IROD1 |
IROD2 |
||||
OR (95% CI) | P-value | OR (95% CI) | P-value | OR (95% CI) | P-value | OR (95% CI) | P-value | |
PDR | 9.32 (2.15, 40.46) | 0.003* | 2.42 (0.96, 6.07) | 0.06 | 0.53 (0.16, 1.79) | 0.31 | 0.73 (0.23, 2.32) | 0.59 |
CKD | 2.59 (1.34, 5.00) | 0.005* | 2.03 (1.21, 3.40) | 7.1 × 10–3* | 1.63 (1.08, 2.46) | 0.02* | 0.85 (0.53, 1.39) | 0.52 |
Neuropathy | 3.30 (1.29, 8.43) | 0.01* | 13.60 (5.20, 35.50) | 1.0 × 10–7* | 2.08 (1.28, 3.37) | 3.0 × 10–3* | 0.70 (0.45, 1.09) | 0.12 |
CVD | 0.61 (0.25, 1.51) | 0.3 | 1.13 (0.60, 2.11) | 0.71 | 1.11 (0.68, 1.8) | 0.68 | 1.44 (0.87, 2.36) | 0.15 |
PDR, proliferative diabetic retinopathy; CKD, chronic kidney disease; CVD, cardiovascular disease; OR, Odds Ratios; 95% CI, 95% confidence intervals; and p-values were calculated using logistic regression adjusted for sex, age, and diabetes duration. *Significant after adjustment for the multiple testing using FDR (<0.05).