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. 2021 Jul 2;9:686675. doi: 10.3389/fcell.2021.686675

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Copyright © 2021 Zhang, Shen, Cai, Yu, Yang, Wu, Zhu and Liu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Heatmap, distribution of risk scores, survival status, and Kaplan–Meier curves of OS for BRCA patients in TCGA training cohort (A) and validation cohort (B). (C) The infiltrating levels of 22 immune cell types in high-/low-risk subtypes. *p < 0.05 and **p < 0.01. (D) Heatmap of correlations between 22 immune cell types with risk scores and clusters. (E) Immune score in the high- and low-risk groups. (F–H) Activated B cell, effector memory CD4 T cell, and neutrophil in two risk groups. OS, overall survival; BRCA, breast cancer; TCGA, The Cancer Genome Atlas.