Table 1.
MiR-200a and lncRNA ANRIL involved in the pathogenesis of various tumors.
miR-200a | ||||
---|---|---|---|---|
Study | Gene-Target | Type of tumor | Biological function | Expression |
Li et al., 2016 [11] | PTEN | Colorectal cancer | Promotes tumor cell proliferation, invasion, migration, and invasion | Up- regulation |
Zuo et al., 2018 [12] | ZEB1 | Breast cancer | Promotes tumor cell invasion and migration | Up- regulation |
Suo et al., 2018 [13] |
PTEN |
Ovarian cancer |
Promotes tumor cell invasion and migration |
Up- regulation |
LncRNA ANRIL | ||||
Study |
Gene-Target |
Type of tumor |
Biological function |
Expression |
Ma et al., 2019 [14] | miR-144 and PBX3 | Hepatocellular carcinoma | Promotes tumor cell proliferation, migration, invasion | Up- regulation |
Deng et al., 2019 [15] | NF-kB | Gastric cancer | Suppresses apoptosis in tumor cell. Promotes tumor growth and tumor cells migration | Up- regulation |
Wu et al., 2018 [16] | SOX2 | Nasopharyngeal carcinoma | Promotes cell proliferation and tumor growth | Up- regulation |
Abbreviation: LncRNA, Long non-coding ribonucleic acid; miRNA, microRNA; PTEN, Validated phosphatase and tensin homolog; ZEB1, Zinc finger E-box binding homeobox 1; PBX3, PBX homeobox 3; NF-kB, Nuclear factor-κB; SOX2, SRY-Box transcription factor 2; LncRNA ANRIL, Long non-coding RNA antisense non-coding RNA in the INK4 locus.